Management and investigation of neonatal encephalopathy: 2017 …
WEBThis review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE). Encephalopathy in neonates can be due to varied aetiologies in addition to hypoxic-ischaemia. A combination of careful history, examination and the judicious use of investigations can help ...
Neonatal high-frequency oscillatory ventilation: where are we now?
WEBHigh-frequency oscillatory ventilation (HFOV) is an established mode of respiratory support in the neonatal intensive care unit. Large clinical trial data is based on first intention use in preterm infants with acute respiratory distress syndrome. Clinical practice has evolved from this narrow population. HFOV is most often reserved for term and preterm infants with severe, and often complex ...
What’s new in the management of neonatal early-onset sepsis?
WEBThe expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they ...
Nucleated red blood cells in the fetus and newborn
WEBAlthough nucleated red blood cells (nRBCs) are rarely found circulating in older children,1 they are commonly seen in the blood of newborns. They are primarily produced in the fetal bone marrow in response to erythropoietin and are stored in the marrow as precursors to reticulocytes and mature erythrocytes. Many acute and chronic stimuli cause increases in the number of circulating nRBCs from ...
WEBa single CRP value for proven sepsis was 64% (95% CI 53 to. 59) with a positive predictive value of only 14% (95% CI 11 to. 17).45 However, if serial CRP values remain normal, there is a low likelihood of infection with a negative predictive value of nearly 100%46 The 2021 NICE guidelines recommend use of.
Heart rate during the first 24 hours in term-born infants
WEBResults The study included 953 infants. The 50th percentile was 126 beats per minute (bpm) at age 2 hours and thereafter 120–122 bpm. The respective 2nd and 98th percentiles were 102 (thereafter 96–100) bpm and 162 (thereafter 150–156) bpm. The mean HR was 5.6 bpm higher when awake than asleep, 4.9 bpm higher when on the mother’s chest ...
Neonatal jaundice in infants born at 37 weeks: is NICE treating too ...
WEBNeonatal jaundice affects approximately 60% of term and 80% of preterm infants within the first week of life. Gestation-based treatment threshold graphs by the National Institute of Health and Care Excellence are used to guide jaundice management in the UK.1 NICE treatment thresholds at 37-week gestation are much lower compared with ≥38 weeks and also when compared with the previous and ...
Impact of the new NICE guidance 2021 on management of early …
WEBIn April 2021, the National Institute for Health and Care Excellence (NICE) published new guidelines for neonatal infection,1 replacing the 2012 guidance. In order to reduce antibiotic usage in healthy infants, NICE modified risk factors and allowed use of Kaiser Permanente Sepsis Risk Calculator (KP-SRC)2 as an alternative with prospective audit. KP-SRC provides recommendations for ...
WEBMar 19, 2020 · REFERENCES 1. Ntusi N, Aubin L, Oliver S, Whitelaw A, Mendelson M. Guideline for the optimal use of blood cultures. SAMJ: South African Medical Journal. 2010;100(12):839-
Homepage | ADC Fetal & Neonatal Edition
WEBs an edition of ADC from BMJ and RCPCH, publishing perinatal & neonatal medicine research and reviews. Archives of Disease in Childhood: Fetal & Neonatal is a Plan S compliant Transformative Journal. Archives of Disease in Childhood is led by Dr Nick Brown, clinician, epidemiologist and international child health expert.