It is an ester-derived prodrug that is converted in vivo by serum and tissue esterases to tenofovir, an acyclic nucleoside phosphonate (nucleotide) that inhibits HIV reverse transcriptase.

Each year, more than 3 million people are diagnosed with cancers driven by mutations in three RAS-family genes: KRAS, NRAS, ...

This article was originally published with the title “ The Nucleotide Sequence of a Nucleic Acid ” in Scientific American Magazine Vol. 214 No. 2 (February 1966), p. 30 doi:10.1038 ...

Two images were stored in and retrieved from DNA sequences faster than ever before. This could be a game-changer for our data ...

What kinds of mutations exist? Mutations aren't just grouped according to where they occur — frequently, they are also categorized by the length of the nucleotide sequences they affect.

Generally, the dual NRTI backbone treatment of combination with a non-NRTI (NNRTI) or protease inhibitor (PI) should comprise a cytidine analogue (lamivudine, emtricitabine) and a thymidine ...

Hope Regional Medical Center in Panama City is now using a powerful new diagnostic tool in the fight against prostate cancer.