In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

The 49ers just lost 23-17 on the road to the Minnesota Vikings. Here are the 49ers' grades for this embarrassment.

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

The San Francisco 49ers certainly did their due diligence this summer as Brandon Aiyuk's future with the team was in question ...

The San Francisco 49ers were reportedly interested in Las Vegas Raiders wide receiver Jakobi Meyers on the trade market ...

Last season, no one cared if Brandon Aiyuk finished a game with two catches for 28 yards. He wasn't the focual point of the ...

NFL legend Peyton Manning ripped San Francisco 49ers wide receiver Brandon Aiyuk for dropping a touchdown catch on Monday ...

Aiyuk missed all of training camp this summer while angling for a new deal with the 49ers. He eventually agreed to a ...

San Francisco 49ers wide receiver Brandon Aiyuk didn't jump at the opportunity to watch the film of his team's 32-19 victory ...

With 15 seconds left in the second quarter at Levi's Stadium, 49ers quarterback Brock Purdy threw what appeared to be a ...

San Francisco 49ers wide receiver Brandon Aiyuk makes his first reception vs. the Minnesota Vikings for a 22-yard gain.

Peyton Manning loses his mind at Brandon Aiyuk for dropping a catch in the end zone and blames it on Aiyuk's contract dispute ...